Current Language EN
English English Türkçe Türkçe Español Español Português Português Pусский Pусский Filipino Filipino Tiếng Việt Tiếng Việt हिन्दी हिन्दी العربية العربية বাংলা বাংলা Deutsch Deutsch 中文 中文
Research Article

The chemical composition of Centaurea furfuracea Coss. and Dur. essential oil with antioxidant, anticholinesterase and antibiofilm activities

2130 reads
Ahmed Elkhalifa Chemsa , Amar Zellagui , Mehmet Öztürk , Ebru Erol , Ozgur Ceylan , Mehmet Emin Duru
J Ong Chem Res, 2018, 3 (2), 54-63, DOI: https://doi.org/10.5281/zenodo.23590585, ISSN 2651-4338
Verified on SciChain · token #21 of SciMatic Articles (ERC-1155, 1,000,000 tokens)
Contract 0x0E596B4b…F05eF8 · mint transaction · verify the record
Proof of record · recorded 2026-10-23 · anchored on SciChain · Verify (opens in a new tab) · record

Abstract

The aim of this work was to conduct the chemical composition of essential oil (EO) of Centaurea furfuraceafrom Algerian Sahara and investigate the antioxidant, anticholinesterase, antimicrobial and antibiofilm activities of its essential oil and methanol extract. EO of C. furfuracea was analyzed by GC and GC-MS. Sixty-nine compounds identified, representing 96.94 % of the total oil. Caryophyllene oxide (12.01 %), Z-10-pentadecen-1-ol (8.11 %), farnesyl methylester (7.79 %) were identified as the main constituents. The antioxidant activity was determined using three complementary assays, in lipid peroxidation inhibition the methanol extract showed the best activity with an IC50 = 28.73 ± 0.29 µg/mL followed by EO with an IC50 = 95.95 ± 15.20 µg/mL. While in DPPH and CUPRAC assays, EO and methanol extract indicated a less to moderate activity. The in vitro anticholinesterase activity, the methanol extract showed moderate inhibitory activities against acetylcholinesterase (IC50= 164.4 ± 5.69 µg/mL) and butyrylcholinesterase (IC50 = 82.4±1.75 µg/mL), while EO was inactive against both enzymes. Minimum inhibitory concentrations (MICs) were calculated by microtitre broth dilution method, and antibiofilm effect by microplate biofilm assay. EO inhibited the growth of all tested microorganisms, MIC values were between 6.25 and 25 µL/mL concentrations, better than methanol extract. The highest antibiofilm activity have reached to 87.90 % with methanol extract of C. furfuracea against Staphylococcus aureus ATCC 6538 Pat 50 mg/mL concentration.These results showed that C. furfuracea is a natural source of active compounds with antibiotic and antibiofilm effects against S. aureusand B. subtilis, and Bacillus cereus, respectively, and also presents antioxidant and anticholinesterase properties.

Keywords antioxidant Antibiofilm Anticholinesterase Centaurea furfuracea Essential oil
Authors 6
View Publication Certificate Order a Printed Certificate For this article's authors: $50.00 ($35.00 to the Philippines), shipping included. View PDF Cite This Article Back to Archives

The team behind this paper

6 authors, 1 institution.

This paper Muğla Muğla 1 author Ahmed Elkhalifa Chemsa — corresponding author AC Ahmed Elkhalifa Chemsa ✉ Amar Zellagui AZ Amar Zellagui Mehmet Öztürk MÖ Mehmet Öztürk Ebru Erol EE Ebru Erol Ozgur Ceylan OC Ozgur Ceylan Mehmet Emin Duru MD Mehmet Emin Duru

5 of them have not recorded an affiliation.

Readership

638 reads over 34 months.

February 2024 November 2026

Related work on SciMatic

Closest of 3 articles sharing keywords with this one. A rarer shared keyword counts for more than a common one.

On SciChain

This article is token #21 of SciMatic Articles (ERC-1155): 1,000,000 tokens, minted once, never more. The chain also stores a fingerprint (SHA-256) of the article's record, so anyone can check that it has not been altered.

HolderWalletTokens
SciMatic 0xc35709…277732 100,000 (10%)
Ahmed Elkhalifa Chemsa 0xc78bcD…Ec9e5F 150,000 (15%)
Amar Zellagui 0xca26ff…350C0E 150,000 (15%)
Mehmet Öztürk 0x6BbbCb…26F260 150,000 (15%)
Ebru Erol 0x696b6B…5bc1A4 150,000 (15%)
Ozgur Ceylan 0x7eeBD8…Cfe085 150,000 (15%)
Mehmet Emin Duru 0xFaeeE8…Eaf143 150,000 (15%)
Content hash 0x968d6ee9a69da5ca0b98fa4f58fcafbae63c95aec0eda24cabb5108251332c3e
View on the explorer Verify the record Mint transaction

Bibliographic Information

Ahmed Elkhalifa Chemsa, Amar Zellagui, Mehmet Öztürk, Ebru Erol, Ozgur Ceylan, Mehmet Emin Duru, (2018). The chemical composition of Centaurea furfuracea Coss. and Dur. essential oil with antioxidant, anticholinesterase and antibiofilm activities, Journal of Ongoing Chemical Research, 3(2): 54-63
Bibtex Citation
@article{ahmed_elkhalifa_chemsa2018jocr,
author = {Ahmed Elkhalifa Chemsa and Amar Zellagui and Mehmet Öztürk and Ebru Erol and Ozgur Ceylan and Mehmet Emin Duru},
title = {The chemical composition of Centaurea furfuracea Coss. and Dur. essential oil with antioxidant, anticholinesterase and antibiofilm activities},
journal = {Journal of Ongoing Chemical Research},
year = {2018},
volume = {3},
number = {2},
pages = {54-63},
doi = {10.5281/zenodo.23590585},
url = {https://scimatic.org/show_manuscript/21}
}
APA Citation
Chemsa, A.E., Zellagui, A., Öztürk, M., Erol, E., Ceylan, O., Duru, M.E., (2018). The chemical composition of Centaurea furfuracea Coss. and Dur. essential oil with antioxidant, anticholinesterase and antibiofilm activities. Journal of Ongoing Chemical Research, 3(2), 54-63. https://doi.org/10.5281/zenodo.23590585

Author Information

  • To change your profile photo, login to scimatic.org, go to your profile and change the photo.
  • Any photo that shows your face will do: we crop it to your head and shoulders and give it a plain background automatically.
  • To sign in, go to Sign in and enter the e-mail address registered with the article: we e-mail you a one-time sign-in link (there is no password).
  • In case of any other problem, contact your editor directly or write to us at info @ scimatic.org