12 the role of phosphatidylinositol-3-kinase and amp-activated kinase in the rapid estrogenic attenuation of cannabinoid-induced changes in energy homeostasis

13 dram1 regulates autophagy and cell proliferation via inhibition of the phosphoinositide 3-kinase-akt-mtor-ribosomal protein s6 pathway

14 cannabinoid receptor 1 signaling in cardiovascular regulating nuclei in the brainstem: a review

15 role of akt isoforms controlling cancer stem cell survival, phenotype and self-renewal

16 role of inositol poly-phosphatases and their targets in t cell biology

17 the composition-tunable polydiacetylenic complex films: conformational change upon thermal stimulation and preferential interaction with specific small molecules

18 pi3k-mtor-s6k signaling mediates neuronal viability via collapsin response mediator protein-2 expression

19 mechanistic target of rapamycin (mtor): a point of convergence in the action of insulin/igf-1 and g protein-coupled receptor agonists in pancreatic cancer cells

20 Anti-diabetic effect of oligosaccharides from seaweed Sargassum confusum via JNK-IRS1/PI3K signalling pathways and regulation of gut microbiota.

21 Anti-tumor efficacy of phellamurin in osteosarcoma cells: Involvement of the PI3K/AKT/mTOR pathway.

22 Towards Enhancing Therapeutic Glycoprotein Bioproduction: Interventions in the PI3K/AKT/mTOR Pathway.

23 MicroRNA-936 targets FGF2 to inhibit epithelial ovarian cancer aggressiveness by deactivating the PI3K/Akt pathway.

24 Novel cytisine derivatives exert anti-liver fibrosis effect via PI3K/Akt/Smad pathway

25 Sika deer antler protein against acetaminophen-induced nephrotoxicity by activating Nrf2 and inhibition FoxO1 via PI3K/Akt signaling.

26 Molecular basis for class side effects associated with PI3K/AKT/mTOR pathway inhibitors.

27 Sotetsuflavone suppresses invasion and metastasis in non-small-cell lung cancer A549 cells by reversing EMT via the TNF-α/NF-κB and PI3K/AKT signaling pathway

28 Model-based in silico analysis of the PI3K/Akt pathway: the elucidation of cross-talk between diabetes and breast cancer

29 Costus root granules improve ulcerative colitis through regulation of TGF-β mediation of the PI3K/AKT signaling pathway.

30 Acacia catechu (L.f.) Willd and Scutellaria baicalensis Georgi extracts suppress LPS-induced pro-inflammatory responses through NF-кB, MAPK, and PI3K-Akt signaling pathways in alveolar epithelial type II cells.

31 Correction: Kaempferol inhibits angiogenesis by suppressing hif-1α and vegfr2 activation via erk/p38 mapk and pi3k/akt/mtor signaling pathways in endothelial cells (Preventive Nutrition and Food Science (2017) 22: 4 (320-326)

32 The PI3K/AKT/mTOR and CDK4/6 pathways in endocrine resistant HR+/HER2- metastatic breast cancer: Biological mechanisms and new treatments

33 16α-Hydroxytrametenolic acid from Poria cocos improves intestinal barrier function through glucocorticoid receptor mediated PI3K/Akt/NF-κB pathway.

34 miR-21-3p inhibits autophagy of bovine granulosa cells by targeting VEGFA via PI3K/AKT signaling.

35 CUDC‑907 reverses pathological phenotype of keloid fibroblasts in vitro and in vivo via dual inhibition of PI3K/Akt/mTOR signaling and HDAC2.

36 Identifying and targeting pathogenic PI3K/AKT/mTOR signaling in IL-6-blockade-refractory idiopathic multicentric Castleman disease.

37 PI3K/AKT/mTOR inhibitors for advanced or recurrent endometrial cancer.

38 A molecular sub-cluster of colon cancer cells with low VDR expression is sensitive to chemotherapy, BRAF inhibitors and PI3K-mTOR inhibitors treatment.

39 ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors.

40 A preliminary report: genistein attenuates cerebral ischemia injury in ovariectomized rats via regulation of the PI3K-Akt-mTOR pathway.

41 DJ-1/PARK7 inhibits high glucose-induced oxidative stress to prevent retinal pericyte apoptosis via the PI3K/AKT/mTOR signaling pathway.

42 Quercetin facilitates cell death and chemosensitivity through RAGE/PI3K/AKT/mTOR axis in human pancreatic cancer cells.

43 Long noncoding RNA HAGLROS promotes the process of mantle cell lymphoma by regulating miR-100/ATG5 axis and involving in PI3K/AKT/mTOR signal

44 Upregulation of lncRNA HAGLROS enhances the development of nasopharyngeal carcinoma via modulating miR-100/ATG14 axis-mediated PI3K/AKT/mTOR signals

45 MicroRNA-183 affects the development of gastric cancer by regulating autophagy via MALAT1-miR-183-SIRT1 axis and PI3K/AKT/mTOR signals

46 Long noncoding RNA HAGLROS regulates apoptosis and autophagy in Parkinson’s disease via regulating miR-100/ATG10 axis and PI3K/Akt/mTOR pathway activation

47 Overexpression of lncRNA ANRIL aggravated hydrogen peroxide-disposed injury in PC-12 cells via inhibiting miR-499a/PDCD4 axis-mediated PI3K/Akt/mTOR/p70S6K pathway

48 2,4-Dihydroxy-3'-methoxy-4'-ethoxychalcone suppresses cell proliferation and induces apoptosis of multiple myeloma via the PI3K/akt/mTOR signaling pathway

49 Rosmarinic acid inhibits proliferation and invasion of hepatocellular carcinoma cells SMMC 7721 via PI3K/AKT/mTOR signal pathway

50 Pharmacological mTOR targeting enhances the antineoplastic effects of selective PI3Kα inhibition in medulloblastoma

51 PI3K/mTOR inhibition of IDH1 mutant glioma leads to reduced 2HG production that is associated with increased survival

52 SOX9/miR-203a Axis Drives PI3K/AKT Signaling to Promote Esophageal Cancer Progression.

53 Selective inhibition of mTORC1/2 or PI3K/mTORC1/2 signaling does not prevent or modify epilepsy in the intrahippocampal kainate mouse model.

54 Roles of PI3K/Akt and c-Jun signaling pathways in human papillomavirus type 16 oncoprotein-induced HIF-1α, VEGF, and IL-8 expression and in vitro angiogenesis in non-small cell lung cancer cells.

55 Vitamin D Deficiency Induces Insulin Resistance and Re-supplementation Attenuates Hepatic Glucose Output Via the PI3K-AKT-FOXO1 Mediated Pathway.

56 Acupuncture Reduces Apoptosis of Granulosa Cells in Rats with Premature Ovarian Failure Via Restoring the PI3K/Akt Signaling Pathway

57 The PI3KCA and AKT Inhibitory Activities of Lour. Fruits and Heartwoods Towards Hela Cells.

58 Pyrazolopyrimide library screening in glioma cells discovers highly potent antiproliferative leads that target the PI3K/mTOR pathway.

59 Triterpenoids from Liquidambar Fructus induced cell apoptosis via a PI3K-AKT related signal pathway in SMMC7721 cancer cells.

60 Antitumor effects of rafoxanide in diffuse large B cell lymphoma via the PTEN/PI3K/Akt and JNK/c-Jun pathways.

61 Low-level laser therapy induces human umbilical vascular endothelial cell proliferation, migration and tube formation through activating the PI3K/Akt signaling pathway

62 miR-20b and miR-451a Are Involved in Gastric Carcinogenesis through the PI3K/AKT/mTOR Signaling Pathway: Data from Gastric Cancer Patients, Cell Lines and Ins-Gas Mouse Model.

63 PSMC6 promotes osteoblast apoptosis through inhibiting PI3K/AKT signaling pathway activation in ovariectomy-induced osteoporosis mouse model.

64 Correction: Discovery of 3-Oxabicyclo[4.1.0]heptane, a Non-nitrogen Containing Morpholine Isostere, and Its Application in Novel Inhibitors of the PI3K-AKT-mTOR Pathway (Journal of Medicinal Chemistry (2019) 62: 15 (6972−6984) DOI: 10.1021/acs.jmedchem.9b00348)

65 Remodeling tumor immune microenvironment via targeted blockade of PI3K-γ and CSF-1/CSF-1R pathways in tumor associated macrophages for pancreatic cancer therapy.

66 Inhibition of MiR-122 Decreases Cerebral Ischemia-reperfusion Injury by Upregulating DJ-1-Phosphatase and Tensin Homologue Deleted on Chromosome 10 (PTEN)/Phosphonosinol-3 Kinase (PI3K)/AKT.

67 Heterozygous p53-R280T Mutation Enhances the Oncogenicity of NPC Cells Through Activating PI3K-Akt Signaling Pathway.

68 Nerve Growth Factor Protects Against Alcohol-Induced Neurotoxicity in PC12 Cells via PI3K/Akt/mTOR Pathway

69 Nerve Growth Factor Protects Against Alcohol-Induced Neurotoxicity in PC12 Cells via PI3K/Akt/mTOR Pathway

70 17β-Estradiol Protects the Retinal Nerve Cells Suppressing TLR2 Mediated Immune-Inflammation and Apoptosis from Oxidative Stress Insult Independent of PI3K

71 The PI3K Pathway in Human Disease

72 association between pi3k/akt/mtor/p70s6k signaling pathway and hepatic fibrosis

73 pi3k-akt-mtor signaling in prostate cancer progression and androgen deprivation therapy resistance

74 enhanced akt phosphorylation of circulating b cells in patients with activated pi3kδ syndrome

75 hmgb1 protects the heart against ischemia–reperfusion injury via pi3k/akt pathway-mediated upregulation of vegf expression

76 rack1 induces chemotherapy resistance in esophageal carcinoma by upregulating the pi3k/akt pathway and bcl-2 expression

77 wnt/β-catenin, carbohydrate metabolism, and pi3k-akt signaling pathway-related genes as potential cancer predictors

78 selenium protects against lps-induced mc3t3-e1 cells apoptosis through modulation of microrna-155 and pi3k/akt signaling pathways

79 [6]-shogaol inhibits α-msh-induced melanogenesis through the acceleration of erk and pi3k/akt-mediated mitf degradation

80 inhibition of epidermal growth factor receptor and pi3k/akt signaling suppresses cell proliferation and survival through regulation of stat3 activation in human cutaneous squamous cell carcinoma

81 apocynin and diphenyleneiodonium induce oxidative stress and modulate pi3k/akt and mapk/erk activity in mouse embryonic stem cells

82 pim kinases and their relevance to the pi3k/akt/mtor pathway in the regulation of ovarian cancer

83 Dehydrocostus lactone inhibits cell proliferation and induces apoptosis by PI3K/Akt/Bad and ERS signalling pathway in human laryngeal carcinoma.

84 the role of pi3k/akt/mtor signaling in gastric carcinoma

85 phytochemicals and pi3k inhibitors in cancer—an insight

86 pi3k/akt/mtor signaling pathway inhibitors in proliferation of retinal pigment epithelial cells

87 contribution of cftr to alveolar fluid clearance by lipoxin a4 via pi3k/akt pathway in lps-induced acute lung injury

88 pi3k/akt signaling pathway and hepatic fibrosis

89 the critical role of il-15-pi3k-mtor pathway in natural killer cell effector functions

90 chlorin e6 prevents adp-induced platelet aggregation by decreasing pi3k-akt phosphorylation and promoting camp production

91 pi3k signalling in b cell and t cell biology

92 atorvastatin represses the angiotensin 2-induced oxidative stress and inflammatory response in dendritic cells via the pi3k/akt/nrf 2 pathway

93 Melanoma cell-derived factors stimulate hyaluronan synthesis in dermal fibroblasts by upregulating HAS2 through PDGFR-PI3K-AKT and p38 signaling.

94 PI3K/mTOR inhibition promotes the regression of experimental vascular malformations driven by PIK3CA-activating mutations

95 PI3K/mTOR inhibition promotes the regression of experimental vascular malformations driven by PIK3CA-activating mutations

96 Exploring the specificity of the PI3K family inhibitor LY294002

97 E2/ER β Enhances Calcineurin Protein Degradation and PI3K/Akt/MDM2 Signal Transduction to Inhibit ISO-Induced Myocardial Cell Apoptosis

98 Multifunctional Nanoparticles Loading with Docetaxel and GDC0941 for Reversing Multidrug Resistance Mediated by PI3K/Akt Signal Pathway

99 The PI3Kδ inhibitor parsaclisib ameliorates pathology and reduces autoantibody formation in preclinical models of systemic lupus erythematosus and Sjӧgren's syndrome

100 Does GSK-3 provide a shortcut for PI3K activation of Wnt signalling?

101 Artemisia Argyi Extract Uses PI3K/MAPK Signaling to Induce Apoptosis in Human Gemcitabine-Resistant Lung Cancer Cells

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