Does GSK-3 provide a shortcut for PI3K activation of Wnt signalling?

Does GSK-3 provide a shortcut for PI3K activation of Wnt signalling?

Daniel Voskas, Ling S Ling, James R Woodgett;Daniel Voskas;Ling S Ling;James R Woodgett;
F1000 Biology Reports 2010 Vol. 2 pp. -
122
woodgett2010f1000does

Abstract

Glycogen synthase kinase-3 (GSK-3) is a well-established downstream component of the phosphatidylinositol 3-kinase (PI3K) signalling pathway but is also a key enzyme in negatively regulating the canonical Wnt/β-catenin signalling pathway. Several ...

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