The PI3KCA and AKT Inhibitory Activities of Lour. Fruits and Heartwoods Towards Hela Cells.
Abstract
To investigated the activities of chloroform fractions at pH 7 of Lour. Fruits and heartwoods (CF-7F and CF-7H) in decrease expression of PI3KCA, Akt-1 and Akt-2 genes towards cervical cancer cell culture (HeLa) experiments in vitro.CF-7F and CF-7H (12.5 and 25 µg/mL) were tested for its potential inhibition on gene expression of and genes by Reverse Transcription-Polymerase Chain Reaction (RT-PCR) method.CF-7F and CF-7H were showed the activity to reduce the expression of and genes.Our results suggest that CF-7F and CF-7H significantly inhibit the expression of and genes.
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76515
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0x95644003c57E6F55A65596E3D9Eac6813e3566dA
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76515
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10.3889/oamjms.2019.317
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Scimatic Chain (ID: 481)
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