Research article
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A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation
Proceedings of the National Academy of Sciences of the United States of America, vol. 91, no. 1, pp. –, 1994
Abstract
Activation of transcription by the promoter-specific factor Sp1 requires coactivators that are tightly associated with the TATA-box-binding protein (TBP) in the TFIID complex. Recent work has shown that the two glutamine-rich activation domains of Sp1, A and B, can interact with at least one compone …
Keywords
- National Center for Biotechnology Information
- NCBI
- NLM
- MEDLINE
- animals
- pubmed abstract
- nih
- national institutes of health
- national library of medicine
- research support
- non-u.s. gov't
- amino acid sequence
- sequence alignment
- Comparative Study
- Cells
- Cultured
- genetic*
- Transcription Factors / metabolism*
- Molecular Sequence Data
- in vitro techniques
- transcription
- sequence homology
- amino acid
- solubility
- transcriptional activation
- structure-activity relationship
- macromolecular substances
- sp1 transcription factor / metabolism*
- dna mutational analysis
- pmid:8278363
- pmc42912
- doi:10.1073/pnas.91.1.192
- g gill
- e pascal
- r tjian
- drosophila melanogaster
- glutamine / chemistry
- sp1 transcription factor / chemistry
- transcription factor tfiid
How to cite
Gill G; Pascal E; Tseng ZH; Tjian R. (1994). A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation. Proceedings of the National Academy of Sciences of the United States of America, 91(1), –. http://www.ncbi.nlm.nih.gov/pubmed/8278363
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