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Research Article

Antimicrobial and Urease Inhibition Activity of Volatile Oil Obtained from Aerial Parts of Thyme (Thymus vulgaris L.)

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Elif Ayşe Erdoğan Eliuz , Yusuf Sıcak
J Ong Chem Res, 2018, 3 (2), 67-70, DOI: https://doi.org/10.5281/zenodo.2555611, ISSN 2651-4338
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Abstract

The demand for T. vulgaris L. (Thyme) and its derivates has became popular since it has many biologically active components such as mainly antimicrobial, antiinflammatory, antioxidant characteristics. Especially, there were many researches on the antimicrobial performance of T. vulgaris L. essential oil. In this study, we analyzed the content of the essential oil of T. vulgaris aerial parts by using GCMS, its antimicrobial activity to some pathogens and urease inhibition activity. The major components of the oil in thyme were thymol (48.80%), γ-terpinene (15.26%), p-cymene (10.35%), linalol (3.87%), β-myrcene (3.20%). Then, The minimum inhibitory concentration (MIC) were determined against Escherichia coli (ATCC 25293), Bacillus subtilis (ATCC 6633), Staphylococcus aureus (ATCC 25925), Pseudomonas aureginosa, Candida albicans and Candida parapsilosis by using spectrophotometric microbroth technique. We showed that microoganisms were inhibited by the essential oil extracted thyme aerial parts at the end of the 24 hours incubation. Highest inhibition were reported against S. aureus (MIC=7.5 µg/mL), while lowest inhibition were found to be C. albicans (MIC=105.3 µg/mL). Also, the antiurease activities were tested against urease enzymes such as thiourea, spectrophotometrically. The essential oil (27.40±0.46%) of thyme showed higher urease inhibition activity than thiourea (23.08±0.19%). Consequently, it clearly suggested that the essential oil from T. vulgaris aerial parts are a potential source of antimicrobial and urease inhibitory ingredients for the drug and food industry.

Keywords Chemical composition Antimicrobial activity Thymus vulgaris Urease inhibition activity Volatile oil
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The team behind this paper

2 authors.

This paper Elif Ayşe Erdoğan Eliuz — corresponding author EE Elif Ayşe Erdoğan Eliuz ✉ Yusuf Sıcak YS Yusuf Sıcak

2 of them have not recorded an affiliation.

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Yusuf Sıcak 0xaCF039…2E49f4 450,000 (45%)
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Bibliographic Information

Elif Ayşe Erdoğan Eliuz, Yusuf Sıcak, (2018). Antimicrobial and Urease Inhibition Activity of Volatile Oil Obtained from Aerial Parts of Thyme (Thymus vulgaris L.), Journal of Ongoing Chemical Research, 3(2): 67-70
Bibtex Citation
@article{elif_ayşe_erdoğan_eliuz2018jocr,
author = {Elif Ayşe Erdoğan Eliuz and Yusuf Sıcak},
title = {Antimicrobial and Urease Inhibition Activity of Volatile Oil Obtained from Aerial Parts of Thyme (Thymus vulgaris L.)},
journal = {Journal of Ongoing Chemical Research},
year = {2018},
volume = {3},
number = {2},
pages = {67-70},
doi = {10.5281/zenodo.2555611},
url = {https://scimatic.org/show_manuscript/115}
}
APA Citation
Eliuz, E.A.E., Sıcak, Y., (2018). Antimicrobial and Urease Inhibition Activity of Volatile Oil Obtained from Aerial Parts of Thyme (Thymus vulgaris L.). Journal of Ongoing Chemical Research, 3(2), 67-70. https://doi.org/10.5281/zenodo.2555611

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