Particulate cartilage under bioreactor-induced compression and shear
Wang N;Grad S;Stoddart MJ;Niemeyer P;Reising K;Schmal H;Südkamp NP;Alini M;Salzmann GM;;
International orthopaedics2014Vol. 38pp. -
215
n2014internationalparticulate
Abstract
The method of MC culture is feasible under in vitro free-swelling and dynamic loading conditions, simulating in vivo posttransplantation. Mechanical stimulation significantly provokes cellular outgrowth and long-term chondrogenic maturation at the mRNA level, whereas histology depicts immature neoti …