A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation
Abstract
Activation of transcription by the promoter-specific factor Sp1 requires coactivators that are tightly associated with the TATA-box-binding protein (TBP) in the TFIID complex. Recent work has shown that the two glutamine-rich activation domains of Sp1, A and B, can interact with at least one compone …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
amino acid sequence
sequence alignment
Comparative Study
Cells
Cultured
genetic*
Transcription Factors / metabolism*
Molecular Sequence Data
in vitro techniques
transcription
sequence homology
amino acid
solubility
transcriptional activation
structure-activity relationship
macromolecular substances
sp1 transcription factor / metabolism*
dna mutational analysis
pmid:8278363
pmc42912
doi:10.1073/pnas.91.1.192
g gill
e pascal
r tjian
drosophila melanogaster
glutamine / chemistry
sp1 transcription factor / chemistry
transcription factor tfiid
Access
Citation
ID:
266920
References
Blockchain Verification
Account:
NFT Contract Address:
0x95644003c57E6F55A65596E3D9Eac6813e3566dA
Article ID:
266920
Unique Identifier:
Network:
Scimatic Chain (ID: 481)
Loading...
Blockchain Readiness Checklist
Authors
Abstract
Journal Name
Year
Title
Creates 1,000,000 NFT tokens for this article
Token Features:
- ERC-1155 Standard NFT
- 1 Million Supply per Article
- Transferable via MetaMask
- Permanent Blockchain Record
Scan with Saymatik Web3.0 Wallet