Effectiveness of Monovalent Rotavirus Vaccine After Programmatic Implementation in Botswana: A Multisite Prospective Case-Control Study
Abstract
Routine RV1 vaccination in Botswana showed effectiveness similar to that in clinical trials in Africa, including against a serotype fully heterotypic to the vaccine. Undernutrition may in part explain the lower rotavirus VE in low-income settings.
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
logistic models
research support
non-u.s. gov't
u.s. gov't
female
male
Child
Infant
Prospective Studies
P.H.S.
preschool
Diarrhea / epidemiology
Genotype
diarrhea / prevention & control*
case-control studies
diarrhea / virology*
hospitalization
rotavirus infections / epidemiology
rotavirus infections / prevention & control*
rotavirus infections / virology
rotavirus vaccines / administration & dosage
rotavirus vaccines / immunology*
vaccine potency
vaccines
attenuated / administration & dosage
attenuated / immunology
malnutrition / epidemiology
rotavirus / immunology
feces / virology
pmid:27059351
doi:10.1093/cid/civ1207
paul a gastañaduy
andrew p steenhoff
david m goldfarb
botswana / epidemiology
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Citation
ID:
117933
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