Comparing de novo assemblers for 454 transcriptome data
Abstract
Transcriptome assemblies are smaller than genome assemblies and thus should be more computationally tractable, but are often harder because individual contigs can have highly variable read coverage. Comparing single assemblers, Newbler 2.5 performed best on our trial data set, but other assemblers w …
Keywords
databases
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
gene expression regulation
animals
pubmed abstract
nih
national institutes of health
national library of medicine
reproducibility of results
research support
non-u.s. gov't
algorithms
female
male
sequence alignment
Comparative Study
Sequence Analysis
genetic*
Base Sequence
Expressed Sequence Tags
Gene Expression Profiling / methods*
DNA / methods*
contig mapping
reference standards
pmid:20950480
pmc3091720
doi:10.1186/1471-2164-11-571
sujai kumar
mark l blaxter
filarioidea / genetics*
gene expression profiling / instrumentation*
temperature*
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116800
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