With the aim of rebuilding the memory of the specialty of Preventive Medicine and Community Medicine (MPC) in Tunisia, through its indexed scientific publications, the objective of this work was to describe the thematic and methodological profile of indexed scientific research, of this specialty over four decades.This is a descriptive bibliometric study of MPC articles, indexed in the Medline database over a 40-year period (1975-2014), and based on their Medline Material Safety Data Sheets (MSDS). All articles of which the first and / or last authors were MPC university hospital teachers, in one of Tunisia's four faculties of medicine, were included. The themes of the publications were defined through the major keywords (Majr), and categorized according to the following five groups: "non-communicable diseases", "communicable diseases", "violence and traumatisms", "management of health services" and "Research and pedagogy".Among 1664 articles captured by the Medline-based documentary request, 594 had as their first authors, teachers of the MPC specialty and 365 articles were eligible for study. The productivity of the specialty of MPC increased from 29 publications between 1975 and 1984, to 167 between 2005 and 2014. The magazine "La Tunisie Médicale" published 37.6% of the articles of this specialty. Four out of ten MPC papers referred to hospital structures and 35% of them were cross-sectional observational studies. Over the decades, an increase in research topics related to "non-communicable diseases" versus "communicable diseases" has been noted in MPC.In Tunisia, research in MPC has been relatively prolific and globally consistent with the health needs of the population (impacted by the epidemiological transition). The orientation of research projects towards community-based proposals, of high methodological level and mobilizing multidisciplinary teams, would be necessary for the improvement of the quality and relevance of publications in MPC.