Research article
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Early prenatal androgenization results in diminished ovarian reserve in adult female rhesus monkeys
human reproduction (oxford, england), vol. 24, no. 12, pp. –, 2009
Abstract
Based on these animals, early PA appears to program an exaggerated decline in ovarian reserve with age, suggesting that epigenetically induced hormonal factors during fetal development may influence the cohort size of ovarian follicles after birth.
Keywords
- National Center for Biotechnology Information
- NCBI
- NLM
- MEDLINE
- animals
- pubmed abstract
- nih
- national institutes of health
- national library of medicine
- pregnancy
- research support
- non-u.s. gov't
- female
- N.I.H.
- Extramural
- d a dumesic
- d h abbott
- macaca mulatta
- prenatal exposure delayed effects*
- gestational age
- recombinant proteins / pharmacology
- ovary / drug effects
- aging / blood
- fertilization in vitro
- virilism / blood
- testosterone propionate / pharmacology
- pmid:19740899
- pmc2777787
- doi:10.1093/humrep/dep324
- m s patankar
- anti-mullerian hormone / blood*
- embryo culture techniques
- follicle stimulating hormone
- human / pharmacology
- oocyte retrieval / statistics & numerical data
- ovary / physiology*
- ovulation induction
- virilism / chemically induced
- virilism / physiopathology*
How to cite
Dumesic DA; Patankar MS; Barnett DK; Lesnick TG; Hutcherson BA; Abbott DH. (2009). Early prenatal androgenization results in diminished ovarian reserve in adult female rhesus monkeys. human reproduction (oxford, england), 24(12), –. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19740899
Ref key
da2009humanearly
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