The CBP co-activator is a histone acetyltransferase
Abstract
The CBP protein acts as a transcriptional adaptor for many different transcription factors by directly contacting DNA-bound activators. One mechanism by which CBP is thought to stimulate transcription is by recruiting the histone acetyltransferase (HAT) P/CAF to the promoter. Here we show that CBP h …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
pubmed abstract
nih
national institutes of health
national library of medicine
cell line
Nuclear Proteins / metabolism*
Transcription Factors / metabolism*
recombinant fusion proteins / genetics
protein binding
recombinant fusion proteins / metabolism
escherichia coli
creb-binding protein
histone acetyltransferases
trans-activators*
saccharomyces cerevisiae proteins*
acetyltransferases / metabolism*
a j bannister
t kouzarides
binding
competitive
cos cells
pmid:8967953
doi:10.1038/384641a0
adenovirus e1a proteins / metabolism
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271246
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