Research article
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Real-world effectiveness and predictors of sustained virological response with all-oral therapy in 21,242 hepatitis C genotype-1 patients
antiviral therapy, vol. 22, no. 6, pp. –, 2017
Abstract
The diversity and size of this cohort allowed for extensive examination of regimen-specific predictors of SVR. FIB-4>3.25 and detectable 4-week on-treatment HCV RNA had the greatest negative impact. African-American race, low or high BMI, and PPIs negatively impacted odds of SVR for LDV/SOF ±RBV. …
Keywords
- Administration
- National Center for Biotechnology Information
- NCBI
- NLM
- MEDLINE
- humans
- pubmed abstract
- nih
- national institutes of health
- national library of medicine
- prognosis
- treatment outcome
- adult
- female
- male
- aged
- middle aged
- Comorbidity
- risk factors
- 80 and over
- drug therapy
- combination
- hepatitis c / diagnosis
- antiviral agents / administration & dosage
- antiviral agents / therapeutic use*
- oral
- hepacivirus / genetics*
- hepatitis c / epidemiology
- hepatitis c / drug therapy*
- sustained virologic response
- genotype*
- hepatitis c / virology*
- lisa i backus
- larry a mole
- pmid:27934775
- doi:10.3851/imp3117
- pamela s belperio
How to cite
Backus LI; Belperio PS; Shahoumian TA; Loomis TP; Mole LA. (2017). Real-world effectiveness and predictors of sustained virological response with all-oral therapy in 21,242 hepatitis C genotype-1 patients. antiviral therapy, 22(6), –. http://www.ncbi.nlm.nih.gov/pubmed/27934775
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li2017antiviralreal-world
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