Research article
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Evaluation of an oral suspension of VP20621, spores of nontoxigenic Clostridium difficile strain M3, in healthy subjects
Antimicrobial agents and chemotherapy, vol. 56, no. 10, pp. –, 2012
Abstract
VP20621, spores of nontoxigenic Clostridium difficile (NTCD) strain M3, is protective against challenge with toxigenic strains in hamsters. Human administration and colonization may prevent primary C. difficile infection (CDI) or recurrent CDI. Healthy adult subjects 18 to 45 years old or ≥60 years …
Keywords
- National Center for Biotechnology Information
- NCBI
- NLM
- MEDLINE
- humans
- pubmed abstract
- nih
- national institutes of health
- national library of medicine
- research support
- non-u.s. gov't
- adult
- female
- male
- adolescent
- middle aged
- young adult
- Randomized Controlled Trial
- Double-Blind Method
- spores
- bacterial / drug effects*
- enterocolitis
- vancomycin / therapeutic use*
- pmid:22850511
- PMC3457387
- doi:10.1128/AAC.00913-12
- Stephen A Villano
- Michael Seiberling
- Dale N Gerding
- Clostridioides difficile / drug effects*
- Clostridioides difficile / pathogenicity*
- Pseudomembranous / prevention & control
How to cite
Villano SA; Seiberling M; Tatarowicz W; Monnot-Chase E; Gerding DN. (2012). Evaluation of an oral suspension of VP20621, spores of nontoxigenic Clostridium difficile strain M3, in healthy subjects. Antimicrobial agents and chemotherapy, 56(10), –. http://www.ncbi.nlm.nih.gov/pubmed/22850511##substances
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sa2012antimicrobialevaluation
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