Evaluation of an oral suspension of VP20621, spores of nontoxigenic Clostridium difficile strain M3, in healthy subjects

Evaluation of an oral suspension of VP20621, spores of nontoxigenic Clostridium difficile strain M3, in healthy subjects

Villano SA;Seiberling M;Tatarowicz W;Monnot-Chase E;Gerding DN;;
Antimicrobial agents and chemotherapy 2012 Vol. 56 pp. -
252
sa2012antimicrobialevaluation

Abstract

VP20621, spores of nontoxigenic Clostridium difficile (NTCD) strain M3, is protective against challenge with toxigenic strains in hamsters. Human administration and colonization may prevent primary C. difficile infection (CDI) or recurrent CDI. Healthy adult subjects 18 to 45 years old or ≥60 years …

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