Pharmacological mechanisms contributing to the clinical efficacy of levosimendan
Abstract
Acute decompensation of chronic heart failure is a direct life-threatening situation with short-term mortality approaching 30%. A number of maladaptive changes are amplified within the cardiovascular system during the progression of chronic heart failure that makes the decompensation phase difficult …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
review
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
chronic disease
pyridazines / metabolism
simendan
pmid:15867949
doi:10.1111/j.1527-3466.2005.tb00158.x
zoltán papp
kálmán csapó
istván edes
heart failure / drug therapy
hydrazones / metabolism
hydrazones / pharmacology*
hydrazones / therapeutic use*
pyridazines / pharmacology*
pyridazines / therapeutic use*
treatment outcome*
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268128
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