Evolution, population structure, and phylogeography of genetically monomorphic bacterial pathogens
Abstract
Genetically monomorphic bacteria contain so little sequence diversity that sequencing a few gene fragments yields little or no information. As a result, our understanding of their evolutionary patterns presents greater technical challenges than exist for genetically diverse microbes. These challenge …
Keywords
Evolution
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
review
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
Bacterial
DNA
Molecular*
genome
Base Sequence
Phylogeny
Polymorphism
mutation
bacterial / genetics
single nucleotide
yersinia pestis / genetics
bacteria / genetics*
salmonella typhi / genetics
pmid:18785837
doi:10.1146/annurev.micro.62.081307.162832
mark achtman
bacteria / pathogenicity*
mycobacterium tuberculosis / genetics
mycobacterium tuberculosis / pathogenicity
salmonella typhi / pathogenicity
yersinia pestis / pathogenicity
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267744
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