Ability of baclofen in reducing alcohol craving and intake: II--Preliminary clinical evidence
Abstract
With the limitations of the low number of individuals evaluated and the open design, this preliminary clinical study supports the preclinical evidence on the effect of baclofen in reducing alcohol intake. The anticraving properties of the drug suggest a possible role of baclofen in the treatment of …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
treatment outcome
research support
non-u.s. gov't
adult
male
middle aged
Drug Administration Schedule
Rats
dose-response relationship
drug
combined modality therapy
ethanol / adverse effects*
alcohol drinking / prevention & control*
alcohol drinking / psychology
motivation*
pmid:10656195
g addolorato
f caputo
g gasbarrini
alcoholism / psychology
alcoholism / rehabilitation*
baclofen / adverse effects
baclofen / therapeutic use*
family therapy
gaba agonists / adverse effects
gaba agonists / therapeutic use*
substance withdrawal syndrome / prevention & control*
substance withdrawal syndrome / psychology
temperance / psychology
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267627
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