Regulation by granulocyte-macrophage colony-stimulating factor and/or steroids given in vivo of proinflammatory cytokine and chemokine production by bronchoalveolar macrophages in response to Aspergillus conidia
Abstract
Production of the proinflammatory cytokines interleukin (IL)-1 alpha and tumor necrosis factor (TNF)-alpha and of the chemotactic chemokine macrophage inflammatory protein (MIP)-1 alpha by bronchoalveolar macrophages (BAMs) from mice in response to Aspergillus conidia was tested after in vivo admini …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
Disease Models
Animal
Comparative Study
Cells
Cultured
macrophages
time factors
drug therapy
combination
alveolar / drug effects
chemokine ccl4
macrophage inflammatory proteins / biosynthesis
down-regulation
tumor necrosis factor-alpha / biosynthesis*
pmid:12599092
doi:10.1086/368383
elmer brummer
marika kamberi
david a stevens
aspergillosis / drug therapy*
aspergillosis / immunology*
bronchoalveolar lavage fluid / immunology*
cortisone / analogs & derivatives*
cortisone / pharmacology
dexamethasone / pharmacology*
granulocyte-macrophage colony-stimulating factor / pharmacology*
interleukin-1 / biosynthesis*
alveolar / immunology*
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267354
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