Research article
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Effect of IRT5 probiotics on dry eye in the experimental dry eye mouse model
PloS one, vol. 15, no. 12, pp. –, 2020
Abstract
In experimental dry eye model, IRT5 probiotics treatment partially improves experimental dry eye by increasing tear secretion which was associated with and influenced by the change in intestinal microbiome. Also, intestinal microbiome may affect the lacrimal gland through a different mechanism other …
Keywords
- Administration
- National Center for Biotechnology Information
- NCBI
- NLM
- MEDLINE
- Mice
- Inbred C57BL
- RNA
- animals
- pubmed abstract
- nih
- national institutes of health
- national library of medicine
- research support
- non-u.s. gov't
- male
- Disease Models
- Animal
- Ribosomal
- tears / physiology
- dry eye syndromes / therapy*
- oral
- probiotics / administration & dosage*
- 16s
- dry eye syndromes / physiopathology
- jin suk ryu
- mee kum kim
- cornea / pathology
- pmid:33259525
- pmc7707591
- doi:10.1371/journal.pone.0243176
- jayoon moon
- conjunctiva / immunology
- conjunctiva / pathology
- cornea / immunology
- dry eye syndromes / pathology
- gastrointestinal microbiome / genetics
- goblet cells / pathology
- real-time polymerase chain reaction
- tumor necrosis factor-alpha / genetics
How to cite
Moon J; Ryu JS; Kim JY; Im SH; Kim MK. (2020). Effect of IRT5 probiotics on dry eye in the experimental dry eye mouse model. PloS one, 15(12), –. https://www.pubmed.gov/33259525/
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j2020ploseffect
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