Differential susceptibility of different cell lines to swine-origin influenza A H1N1, seasonal human influenza A H1N1, and avian influenza A H5N1 viruses

Differential susceptibility of different cell lines to swine-origin influenza A H1N1, seasonal human influenza A H1N1, and avian influenza A H5N1 viruses

Li IW;Chan KH;To KW;Wong SS;Ho PL;Lau SK;Woo PC;Tsoi HW;Chan JF;Cheng VC;Zheng BJ;Chen H;Yuen KY;;
journal of clinical virology : the official publication of the pan american society for clinical virology 2009 Vol. 46 pp. -
303
iw2009journaldifferential

Abstract

Cell line growth characteristics of S-OIV, sH1N1 and H5N1 appear to correlate clinically and pathologically with involved anatomical sites and severity. Low replication of S-OIV in PK-15 suggests that this virus is more adapted to human than swine.

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