The purpose of this research is to examine the influence of organizational commitment as mediating variable in relation between job satisfaction and intent to leave. The samples were nurses those working at DKT, Panti Rapih, Bethesda, and PKU Muhammadiyah hospital’s in Jogjakarta. Of the 126 questionnaires were distributed to the nurses, 107 data that can employ on this study. The data were collected use 4-item job satisfaction, 6-item for each three dimension organizational commitment, 3-itemintnt to leave. The overall instruments those used in this study were perceptive instruments. Simple regression analysis was used to examine the influence independent variable to dependent variable. Regression analysis (Ballon and Kenny Model’s) was used to examine whether organizational commitment become mediating variable in relation between job satisfaction and intent to leave.