Insights into the development of polycystic ovary syndrome (PCOS) from studies of prenatally androgenized female rhesus monkeys

Insights into the development of polycystic ovary syndrome (PCOS) from studies of prenatally androgenized female rhesus monkeys

Abbott DH;Dumesic DA;Eisner JR;Colman RJ;Kemnitz JW;;
trends in endocrinology and metabolism: tem 1998 Vol. 9 pp. -
246
dh1998trendsinsights

Abstract

The developmental pathophysiology of polycystic ovary syndrome (PCOS) is unknown. However, prenatally androgenized female rhesus monkeys exhibit ovarian and endocrinological features that mimic those found in women with PCOS. Thus, prenatal androgen excess may provide an etiology for hyperandrogenis …

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