Respiratory virus infection of peripheral blood monocytes: correlation with ageing of cells and interferon production in vitro
Abstract
The ability of respiratory syncytial virus (RSV) and parainfluenza virus type 3 (PIV3) to replicate in peripheral blood monocytes cultured in vitro for 1, 2, 4 or 7 days prior to infection was investigated. Inoculation of 1-day old monocytes produced at least tenfold less new virus than infection of …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
u.s. gov't
P.H.S.
Cells
Cultured
Viral
virus replication
monocytes / microbiology*
cytopathogenic effect
k mcintosh
respiratory syncytial viruses / physiology*
parainfluenza virus 3
human / physiology*
pmid:3035067
doi:10.1099/0022-1317-68-6-1749
l r krilov
r m hendry
cell survival
interferon type i / biosynthesis*
monocytes / cytology
monocytes / metabolism
respirovirus / physiology*
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117939
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