Role of T lymphocyte subsets in the pathogenesis of primary infection and rechallenge with respiratory syncytial virus in mice
Abstract
The role of CD4+ and CD8+ T lymphocytes in terminating respiratory syncytial virus (RSV) replication, causing disease, and protecting from reinfection was investigated using a BALB/c mouse model in which CD4+ or CD8+ lymphocytes or both were depleted by injections of Mab directed against the respect …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
u.s. gov't
female
P.H.S.
Antigens
Inbred BALB C
respiratory syncytial viruses / immunology*
lung / pathology
lung / microbiology
virus replication
respirovirus infections / immunology*
respirovirus infections / etiology
b s graham
l a bunton
d t karzon
nose / microbiology
respirovirus infections / pathology
pmid:1909350
pmc295511
doi:10.1172/jci115362
differentiation
t-lymphocyte / analysis
cd4 antigens / analysis
cd8 antigens
t-lymphocyte subsets / physiology*
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115805
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