Pneumolysin polymerase chain reaction for diagnosis of pneumococcal pneumonia and empyema in children
Abstract
Streptococcus pneumoniae is the most important cause of childhood pneumonia and empyema, yet the diagnosis of pneumococcal infections by conventional methods is challenging. In this study, the clinical value of the pneumolysin-targeted real-time polymerase chain reaction (PCR) method for the diagnos …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
Child
preschool
DNA
sensitivity and specificity
Evaluation Study
Bacterial / analysis
Polymerase Chain Reaction / methods*
empyema
pleural effusion / microbiology*
pneumonia
pneumococcal / diagnosis*
pneumococcal / microbiology
bacterial proteins / genetics
streptococcus pneumoniae / genetics*
streptolysins / genetics
j mertsola
pmid:17089094
doi:10.1007/s10096-006-0225-9
e lahti
j jalava
bacterial proteins / blood
pleural / diagnosis*
pleural / microbiology
pleural effusion / genetics
streptolysins / blood*
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114342
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