The transcriptional coactivators p300 and CBP are histone acetyltransferases
Abstract
p300/CBP is a transcriptional adaptor that integrates signals from many sequence-specific activators via direct interactions. Various cellular and viral factors target p300/CBP to modulate transcription and/or cell cycle progression. One such factor, the cellular p300/CBP associated factor (PCAF), p …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
pubmed abstract
nih
national institutes of health
national library of medicine
amino acid sequence
Nuclear Proteins / metabolism*
Transcription Factors / metabolism*
Molecular Sequence Data
transcription
phosphorylation
protein structure
tertiary
viral proteins / metabolism
creb-binding protein
nuclear proteins / chemistry
trans-activators*
transcription factors / chemistry
nucleosomes / chemistry
genetic / physiology*
acetyltransferases / metabolism*
v v ogryzko
y nakatani
acetylation
lysine / metabolism
pmid:8945521
doi:10.1016/s0092-8674(00)82001-2
r l schiltz
adenoviridae / enzymology
histones / chemistry
histones / metabolism*
nucleosomes / enzymology
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273791
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