Clinical and neurophysiological study of the effects of multiple doses of artemisinin on brain-stem function in Vietnamese patients
Abstract
The qinghaosu (artemisinin) group of drugs is the most important new class of antimalarials developed in the last fifty years. Although there has been no clinical evidence of neurotoxicity, an unusual pattern of damage to specific brain-stem nuclei has been reported in experimental animals receiving …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
adult
female
male
adolescent
aged
middle aged
Child
Infant
Drug Administration Schedule
preschool
case-control studies
mefloquine / administration & dosage
antimalarials / therapeutic use
malaria / drug therapy
malaria / epidemiology
antimalarials / administration & dosage
vietnam / epidemiology
neurologic examination
evoked potentials
artemisinins*
auditory
brain stem / drug effects*
mefloquine / therapeutic use
sesquiterpenes / therapeutic use
t t hien
pmid:11357994
doi:10.4269/ajtmh.2000.63.48
e kissinger
j j farrar
antimalarials / pharmacology*
mefloquine / pharmacology*
sesquiterpenes / administration & dosage
sesquiterpenes / pharmacology*
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