WIF1, a component of the Wnt pathway, is down-regulated in prostate, breast, lung, and bladder cancer
Abstract
To detect novel Wnt-pathway genes involved in tumourigenesis, this study analysed the RNA expression levels of 40 genes of the Wnt pathway by chip hybridization of microdissected matched pairs of 54 primary prostate carcinomas. Eleven genes showed greater than two-fold differential expression in at …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
male
aged
middle aged
Genes
Gene Expression Regulation*
statistics
nonparametric
oligonucleotide array sequence analysis
biomarkers
tumor / analysis*
breast neoplasms / chemistry
blotting
transcription factors / genetics
reverse transcriptase polymerase chain reaction
adaptor proteins
signal transducing
immunohistochemistry / methods
transcription factors / analysis*
tumor suppressor*
pmid:14517837
doi:10.1002/path.1449
christoph wissmann
peter johannes wild
christian pilarsky
northern / methods
lung neoplasms / chemistry
neoplasms / chemistry*
prostatic neoplasms / chemistry
repressor proteins
urinary bladder neoplasms / chemistry
Citation
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272532
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