Effects of sofosbuvir-based treatment, with and without interferon, on outcome and productivity of patients with chronic hepatitis C
Abstract
On the basis of an analysis of 2 large clinical trials (FUSION and NEUTRINO), patient outcome and productivity are more negatively affected by the inclusion of pegylated interferon in treatment than by interferon-free regimens. Patients with sustained virologic responses 12 weeks after treatment had …
Keywords
hepatitis c
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
treatment outcome
research support
non-u.s. gov't
Surveys and Questionnaires
randomized controlled trials as topic
efficiency
Genotype
antiviral agents / therapeutic use*
ribavirin / therapeutic use
hepacivirus / isolation & purification
chronic / drug therapy*
quality of life
hepacivirus / classification
hepacivirus / genetics
maria stepanova
zobair m younossi
sharon hunt
pmid:24316172
doi:10.1016/j.cgh.2013.11.032
interferons / therapeutic use*
sofosbuvir
uridine monophosphate / analogs & derivatives*
uridine monophosphate / therapeutic use
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271821
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