Obesity and sex steroid changes across puberty: evidence for marked hyperandrogenemia in pre- and early pubertal obese girls
Abstract
Peripubertal obesity is associated with hyperandrogenemia and hyperinsulinemia throughout puberty, being especially marked shortly before and during early puberty. P and T concentrations in normal-weight Tanner 1-3 girls increase overnight, with similar but less evident changes in obese girls.
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
female
N.I.H.
Extramural
adolescent
Child
Cross-Sectional Studies
Body Weight
hyperandrogenism / metabolism*
progesterone / blood
hydrocortisone / blood
testosterone / blood*
insulin / blood
puberty / blood*
circadian rhythm
hyperinsulinism / metabolism
hyperinsulinism / physiopathology
obesity / physiopathology
obesity / metabolism*
hyperandrogenism / physiopathology
pmid:17118995
pmc2196134
doi:10.1210/jc.2006-2002
christopher r mccartney
susan k blank
john c marshall
Citation
ID:
270795
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