The cAMP-regulated transcription factor CREB interacts with a component of the TFIID complex
Ferreri K;Gill G;Montminy M;;
Proceedings of the National Academy of Sciences of the United States of America1994Vol. 91pp. -
284
k1994proceedingsthe
Abstract
cAMP regulates the expression of a number of genes through the protein kinase A-mediated phosphorylation of CREB at Ser-133. The effects of Ser-133 phosphorylation appear to be primarily transmitted through a modulatory kinase-inducible domain in CREB that functions cooperatively with a 120-amino ac …