National Center for Biotechnology Information NCBI NLM MEDLINE genetic humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't amino acid sequence conserved sequence Comparative Study P.H.S. cell line x wang enhancer elements genetic* DNA-Binding Proteins / metabolism* Nuclear Proteins / metabolism* Receptors Transcription Factors / metabolism* Molecular Sequence Data Promoter Regions transcription sequence homology amino acid kinetics transfection transcription factors / chemistry* gene expression* binding sites mutagenesis sterol regulatory element binding protein 1 point mutation chloramphenicol o-acetyltransferase / biosynthesis leucine zippers* ldl / genetics* sterols / pharmacology* nuclear proteins / chemistry c yokoyama ccaat-enhancer-binding proteins* helix-loop-helix motifs* site-directed pmid:7903453 pmc48032 doi:10.1073/pnas.90.24.11603 x hua dna-binding proteins / chemistry* hydroxymethylglutaryl-coa synthase / biosynthesis hydroxymethylglutaryl-coa synthase / genetics* ldl / biosynthesis sterol regulatory element binding protein 2