Tumor resistance to ferroptosis driven by Stearoyl-CoA Desaturase-1 (SCD1) in cancer cells and Fatty Acid Biding Protein-4 (FABP4) in tumor microenvironment promote tumor recurrence

Tumor resistance to ferroptosis driven by Stearoyl-CoA Desaturase-1 (SCD1) in cancer cells and Fatty Acid Biding Protein-4 (FABP4) in tumor microenvironment promote tumor recurrence

Luis G;Godfroid A;Nishiumi S;Cimino J;Blacher S;Maquoi E;Wery C;Collignon A;Longuespée R;Montero-Ruiz L;Dassoul I;Maloujahmoum N;Pottier C;Mazzucchelli G;Depauw E;Bellahcène A;Yoshida M;Noel A;Sounni NE;;
Redox biology 2021 Vol. 43 pp. -
219
g2021redoxtumor

Abstract

This finding unveils that it is worth taking advantage of tumor lipid addiction, as a tumor vulnerability to design novel treatment strategy to prevent cancer recurrence.

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Ref Key: g2021redoxtumor
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