Promoter selective transcriptional synergy mediated by sterol regulatory element binding protein and Sp1: a critical role for the Btd domain of Sp1
Abstract
Cellular cholesterol and fatty acid levels are coordinately regulated by a family of transcriptional regulatory proteins designated sterol regulatory element binding proteins (SREBPs). SREBP-dependent transcriptional activation from all promoters examined thus far is dependent on the presence of an …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Drosophila
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
u.s. gov't
amino acid sequence
P.H.S.
genetic*
DNA-Binding Proteins / metabolism*
Nuclear Proteins / metabolism*
Transcription Factors / metabolism*
Molecular Sequence Data
Promoter Regions
transcription
dna / metabolism
binding sites
sterol regulatory element binding protein 1
leucine zippers*
drosophila proteins*
transcription factors / chemistry
ccaat-enhancer-binding proteins*
helix-loop-helix motifs*
sp1 transcription factor / metabolism*
sp1 transcription factor / chemistry
pmid:9271397
pmc232370
doi:10.1128/mcb.17.9.5193
j n athanikar
h b sanchez
t f osborne
dna-binding proteins / chemistry
sp3 transcription factor
zinc fingers
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Citation
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267081
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