Percutaneous celiac plexus neurolysis is an effective method to relieve pain in advanced abdominal cancer, especially in patients with pancreatic carcinoma. It was performed a percutaneous celiac plexus neurolysis, using the anterior transgastric route, under general anesthesia and apneic oxygenation in a patient with an advanced pancreatic adenocarcinoma and chronic abdominal pain refractory to clinical treatment. A color Doppler ultrasound detectable flow at the tip of a Turner-22G needle through continuous injection of saline solution was produced. This technique showed the exact position of the needle dynamically during its progression. Then, 30 ml of ethanol was infused into the preaortic space. The procedure took around eight minutes, and the patient expressed significant pain relief and decrease in his narcotic analgesics requirements.