In order to assess the effects of wastewater of Iran Mayeh company on some morphological characteristics and yield of wheat, a factorial experiment based on randomized complete block design (RCBD) was conducted in three replications during 2012-13. The first factor comprised of irrigation times in 3 levels (I1= once irrigation with concentrations of wastewater, I2= twice irrigation with given concentrations of wastewater, I3= irrigation in whole of plant growth period with given concentrations of wastewater) and the second factor comprised of wastewater concentration in 6 levels  included P0= irrigation with well water (control), P15=15% wastewaters +85% well water, P30= 30% wastewaters +70% well water, P45= 45% wastewaters +55% well water, P60= 60% wastewaters +40% well water, P100= 100% wastewater. The results showed that the irrigation in whole of plant growth period (three times) with given concentrations of wastewater compared to once and twice irrigation with wastewater increased biological yield by 28% and 14.6%, respectively. Therefore, based on the results of farm data, using wastewater of leaven plant (Iran Mayeh Co.) for once,  twice and three times irrigation with given concentrations often had an additive effect on some morphological characters include plants height, peduncle length, ear length, and finally biological yield. However, it seems that further studies will be necessary for more than 3 times irrigation and its effects on soil properties.