Objective: Examining the interrelationship between quality of life, hardiness, selfefficacy and self-esteem among working (professional and non-professional), and non-working married women has motivated the researcher to launch this study. Method: The samples in the present study consisted of 250 married employed women and 250 married unemployed women in the age range of 24-41 years old belonging to lower, middle, and upper socioeconomic status groups, with educational qualification of 10±2 and above and having at least one school child. Stratified convenience sampling technique was used for the selection of the sample. The World Health Organization -Quality of Life (WHO QOL) – BREF, the Personal View Survey (PVS), the General Self-Efficacy Scale (GSE), The Coopersmith Self-Eesteem Inventory (CSEI) and demographic questionnaire Sheet were chosen for collection of the data. Results: Obtained Pearson r values revealed significant positive interrelationship between quality of life, hardiness, self-efficacy, and self-esteem in the whole sample, within the subgroups of professional and non-professional employed and unemployed women. Obtained pearson r values revealed significant negative relationship between employment and the above variables in women. Conclusion: It indicates that women with higher quality of life score rank also higher on hardiness, self-efficacy, and self-esteem and vice versa.