Prenatal androgen excess negatively impacts body fat distribution in a nonhuman primate model of polycystic ovary syndrome
Abstract
Prenatal androgenization in female rhesus monkeys induces adiposity-dependent visceral fat accumulation, and late gestation androgenization causes increased total body and non-visceral fat mass. Early gestation androgenization induces visceral fat-dependent hyperinsulinemia. The relationship between …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
pubmed abstract
nih
national institutes of health
national library of medicine
pregnancy
treatment outcome
research support
female
N.I.H.
Extramural
Tomography
Insulin Resistance*
d h abbott
absorptiometry
photon
body composition / physiology
x-ray computed
case-control studies
macaca mulatta
prenatal exposure delayed effects*
polycystic ovary syndrome / complications*
pmid:17471299
pmc2597033
doi:10.1038/sj.ijo.0803638
c m bruns
s t baum
androgens / administration & dosage
androgens / adverse effects*
body composition / drug effects*
body fat distribution*
glucose tolerance test / methods
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119963
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