Increased expression of the N protein of respiratory syncytial virus stimulates minigenome replication but does not alter the balance between the synthesis of mRNA and antigenome
Abstract
A popular model for RNA synthesis by nonsegmented negative-strand RNA viruses is that transcription and RNA replication are executed by the same polymerase complex and that there is a dynamic balance between the two processes that is mediated by the nucleocapsid N protein. According to this model, t …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
RNA
humans
pubmed abstract
nih
national institutes of health
national library of medicine
Cultured
DNA
genome
genetic*
Viral
Recombinant Fusion Proteins / biosynthesis
time factors
complementary
transcription
kinetics
hn protein*
viral envelope proteins
p l collins
viral / biosynthesis*
transfection
respiratory syncytial viruses / genetics
tumor cells
respiratory syncytial viruses / physiology*
viral proteins / metabolism
pmid:9299631
doi:10.1006/viro.1997.8734
r fearns
m e peeples
capsid / biosynthesis
chloramphenicol o-acetyltransferase
nucleocapsid / biosynthesis
nucleocapsid / physiology*
replicon*
viral proteins / biosynthesis
virus replication*
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119422
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