Androgen metabolism in adipose tissue: recent advances

Androgen metabolism in adipose tissue: recent advances

Blouin K;Veilleux A;Luu-The V;Tchernof A;;
molecular and cellular endocrinology 2009 Vol. 301 pp. -
280
k2009molecularandrogen

Abstract

Androgens modulate adipocyte function and affect the size of adipose tissue compartments in humans. Aldo-keto reductase 1C (AKR1C) enzymes, especially AKR1C2 and AKR1C3, through local synthesis and inactivation of androgens, may be involved in the fine regulation of androgen availability in adipose …

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