National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine prognosis research support non-u.s. gov't adult female male age factors aged middle aged Prospective Studies risk factors Tomography x-ray computed meningitis prevalence martijn weisfelt diederik van de beek jan de gans pneumococcal / mortality* morbidity glasgow coma scale pmid:16426988 doi:10.1016/s1474-4422(05)70288-x community-acquired infections pneumococcal / complications pneumococcal / pathology* pneumococcal / therapy