Subcutaneous adipose cell size and distribution: relationship to insulin resistance and body fat
Abstract
Recruitment of adipose cells is required for expansion of body fat mass beyond BMI of 25 kg/m2 . Insulin resistance is associated with accumulation of small adipose cells and enlargement of large adipose cells. These data support the notion that impaired adipogenesis may underlie insulin resistance.
Keywords
biopsy
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
adult
female
male
N.I.H.
Extramural
middle aged
Obesity / metabolism
linear models
Insulin Resistance*
body mass index
Blood Glucose / metabolism
multivariate analysis
adipogenesis
adipocytes / cytology*
insulin / metabolism
pmid:23666871
pmc4344365
doi:10.1002/oby.20209
t mclaughlin
c lamendola
s w cushman
cell size
healthy volunteers
overweight / metabolism
subcutaneous fat / cytology*
subcutaneous fat / metabolism
triglycerides / metabolism
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114247
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