Emergence of fluoroquinolone-resistant Escherichia coli in fecal flora of cancer patients receiving norfloxacin prophylaxis
Abstract
We studied 122 stool samples collected from 25 patients with hematologic malignancies who received prophylactic norfloxacin. Fecal samples were obtained at admission and twice weekly thereafter during prophylaxis. Fluoroquinolone-resistant Escherichia coli strains were isolated from the feces of 10 …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
gel
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
adult
female
male
adolescent
aged
middle aged
Comparative Study
DNA
Bacterial / analysis
Feces / microbiology*
drug resistance
acute disease
electrophoresis
pulsed-field
escherichia coli / drug effects*
microbial / genetics
neoplasms / microbiology
j carratalà
f gudiol
anti-infective agents / therapeutic use*
pmid:8834911
pmc163147
doi:10.1128/aac.40.2.503
a fernandez-sevilla
anti-infective agents / pharmacology
escherichia coli / genetics
leukemia / drug therapy
lymphoma / drug therapy
multiple myeloma / drug therapy
neoplasms / drug therapy*
norfloxacin / therapeutic use*
opportunistic infections / prevention & control*
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112964
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