Pharmacodynamics of intravenous ciprofloxacin in seriously ill patients
Abstract
Seventy-four acutely ill patients were treated with intravenous ciprofloxacin at dosages ranging between 200 mg every 12 h and 400 mg every 8 h. A population pharmacokinetic-pharmacodynamic analysis relating drug exposure (and other factors) to infectious outcome was performed. Plasma samples were o …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
treatment outcome
algorithms
adult
female
male
aged
middle aged
Drug Administration Schedule
Prospective Studies
80 and over
Clinical Trial
multivariate analysis
ciprofloxacin / therapeutic use
ciprofloxacin / pharmacology*
analysis of variance
ciprofloxacin / pharmacokinetics
probability
pmid:8517694
pmc187901
doi:10.1128/aac.37.5.1073
a forrest
d e nix
j j schentag
bacterial infections / drug therapy
critical illness
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112562
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