High pneumococcal DNA loads are associated with mortality in Malawian children with invasive pneumococcal disease
Abstract
Pneumococcal DNA loads are associated with plasma cytokine concentrations, and are higher in meningitis than in pneumonia. High blood and CSF pneumococcal DNA loads are associated with a fatal outcome.
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
female
male
adolescent
Child
Infant
Prospective Studies
preschool
DNA
cytokines / blood
pneumonia
meningitis
pneumococcal / microbiology
streptococcus pneumoniae / genetics
streptococcus pneumoniae / isolation & purification*
bacterial / analysis*
pneumococcal vaccines / immunology
bacterial / blood
bacterial / cerebrospinal fluid
pmid:17468652
pmc2810843
doi:10.1097/01.inf.0000260253.22994.61
enitan d carrol
malcolm guiver
c anthony hart
cytokines / cerebrospinal fluid
malawi / epidemiology
pneumococcal / mortality*
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Citation
ID:
111672
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