Purpose This clinical focus article will highlight the importance of vocabulary instruction, in particular, thinking about instruction in terms of focusing students' attention on words and their uses. Vocabulary knowledge that supports literacy and academic learning is extensive and multidimensional. Many learners accumulate high-quality vocabulary knowledge independently, through wide reading and rich language environments that provide abundant practice with words and language forms. However, instruction in vocabulary provides a more efficient way of getting that job done, especially for learners who are less likely to be experiencing rich language interactions, for example, because they struggle with reading and do little of it on their own. Method Three aspects of vocabulary instruction, choosing words to teach, the inclusion of morphological information, and the importance of engaging students in interactions around words, will be explored. Considerations in choosing words include their role in the language and their utility to students. Morphology will be discussed in terms of using Latin roots in instruction as a resource for unlocking new word meanings and a framework for understanding language. Conclusion Effective instruction means bringing students' attention to words in ways that promote not just knowing word meanings but also understanding how words work and how to utilize word knowledge effectively.