Symplekin and xGLD-2 are required for CPEB-mediated cytoplasmic polyadenylation

Symplekin and xGLD-2 are required for CPEB-mediated cytoplasmic polyadenylation

Barnard DC;Ryan K;Manley JL;Richter JD;;
Cell 2004 Vol. 119 pp. -
287
dc2004cellsymplekin

Abstract

Cytoplasmic polyadenylation-induced mRNA translation is a hallmark of early animal development. In Xenopus oocytes, where the molecular mechanism has been defined, the core factors that control this process include CPEB, an RNA binding protein whose association with the CPE specifies which mRNAs und …

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