Ecocities can provide solutions for the improvement of human settlements around the world and the living conditions therein, but in the authors’ experience, only as long as they are able to address the following questions correctly: How to formulate an ecocity concept that, considering issues of general concern, can be at the same time adapted to different local conditions? What are the instruments supporting the development and implementation of ecocity solutions? VTT’s EcoCity concept for sustainable community and neighbourhood regeneration and development has been designed in response to the first question. Likewise, specific methodologies and effective facilitation processes and skills have been developed in response to the second question. Since the methodologies have been discussed in a previous scientific article, the present one focuses on the facilitation processes and skills, and also on other related, fundamental aspects like participation, adaptation, capacity building, etc. Facilitation processes supporting EcoCity development require matching “hard” and “soft” skills in a fluid way. The main findings are discussed with the help of two case studies: one in Medellín (Colombia), and the other one in Zambia.