This study focused on examination impact of Profit Sharing Ratio (NSM) to Mudharabah savings in Indonesia Syariah Bank. The model used in this study is the Multiple Linear Regression OLS methods (Ordinary Least Square) with the time series data in period 2004.1-2009.2. But in this model, we also considerd Gross Domestic Product (PDB), Deposit Interest Rate (RSK), and Inflation (INF) as control variables. The results of the research are variables of Profit Sharing Ratio (NSM), Deposit Interest Rate (RSK) and Inflation (INF) are affected not statistically affected Mudharabah Savings. The other side, the variable of Gross Domestic Product (GDP) statistically affects Mudharabah Savings. The interest of people on Mudharabah Savings is not because of the Profit Sharing Ratio that become the main determinant in Mudharabah Saving but of the more Islamic System.